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Nobuyuki Tajima Selected Research

JTE 607

3/2010JTE-607, a multiple cytokine production inhibitor, induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.
10/2006JTE-607, a multiple cytokine production inhibitor, ameliorates disease in a SCID mouse xenograft acute myeloid leukemia model.

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Nobuyuki Tajima Research Topics

Disease

2Neoplasms (Cancer)
07/2011 - 11/2007
2Leukemia
03/2010 - 10/2006
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
03/2010 - 10/2006
1Arthritis (Polyarthritis)
05/2012
1Rheumatoid Arthritis
05/2012
1Colorectal Neoplasms (Colorectal Cancer)
07/2011
1Cytokine Release Syndrome
03/2010
1Carcinogenesis
11/2007
1Colonic Neoplasms (Colon Cancer)
11/2007

Drug/Important Bio-Agent (IBA)

2trametinibIBA
05/2012 - 07/2011
2CytokinesIBA
03/2010 - 10/2006
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2010 - 10/2006
2JTE 607IBA
03/2010 - 10/2006
1Leflunomide (Arava)FDA LinkGeneric
05/2012
1Mitogen-Activated Protein KinasesIBA
05/2012
1Phosphotransferases (Kinase)IBA
05/2012
1Collagen Type II (Type II Collagen)IBA
05/2012
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
05/2012
1Indicators and Reagents (Reagents)IBA
05/2012
1Messenger RNA (mRNA)IBA
03/2010
1N- (3- (5- (4- bromo- 2- fluorophenylamino)- 3- cyclopropyl- 8- methyl- 2,4,7- trioxo- 3,4,7,8- tetrahydro- 2H- pyrido(2,3- d)pyrimidin- 1- yl)phenyl)methanesulfonamideIBA
11/2007
1Cyclin-Dependent Kinases (cdk Proteins)IBA
11/2007
1Cyclin-Dependent Kinase Inhibitor p16IBA
11/2007
1pyrimidineIBA
11/2007
1Cytarabine (Cytosar-U)FDA LinkGeneric
10/2006

Therapy/Procedure

1Oral Administration
07/2011